FYI - this was created as an article rather than a question. Make sure to select "Ask a Question" rather than "Create an article" in the future so they're easier to track and find.
To answer your question I looked at some support questions and they were directed to the following answers post:
It looks like we support monitoring applications running IPv6 but it is NOT supported for client-server-collector communication. These were from older versions but I have not seen any changes in 6.5 so I believe this is still the case.
Sorry, that I created post as article, how I could convert it to "Ask a Question"?
I mean what if my AppMon components (DT Server, Memory Analysis, DB, Collectors, agents) will use IPv6? Does this case support by dynatrace configuration?