The question is about what agents are there and what is configuration of your agent groups. . Net agents should have special set of built in sensors, iis as well. This is related to other technologies as well. Best way for adding agent groups is using wizard. Tell us about your technology stack, sensor placement configuration. Do you use separate agent groups for iis and .net etc.
Those agents are IIS, or .net services? If IIS you need web server instrumentation as well.
Remember about enabling Appmon primary agent (Dynatrace web server agent service).
So I assume that those are .net services, you have to create entry point sensors (dev team should tell you what are starting points methods + class). You can make cpu sampling for investigation as well.