What is the best approach to reconfigure a already installed OneAgent without re-installationChanging the typical parameters that you would set during installation:
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I would offer that a re-installation would be the safer, supported (and probably quicker) option to make the above changes.
But otherwise, in a windows environment, the first three parameters can be found in "../Program Files/Dynatrace/oneagent/conf/ruxitagent.conf"
For Linux "/opt/dynatrace/oneagent/conf/ruxitagent.conf" or similar
Digging around, I can't find where the INFRA_ONLY flag is stored. I did however dig up this answer which talks about making those changes within Dynatrace (needs to be enabled globally & then can be set per host).
Hope that's helpful.