What kind of support do you need? Tracing through the protocol? Monitoring some counters on the application production or consuming messages? It really varies, but there not any direct support for any protocol within Dynatrace. Dynatrace support is based on particular libraries/frameworks/applications.
Please describe your use case with more details and most likely there is a solution how to solve your issue.
Well, it all depends on your application/library used.
For monitoring service connections, you can use custom service and request attributes to capture your requests. But this will require knowledge of the library used in your application to known where to put the custom service.
For TCP connections / monitoring ports you can for example check that using a script and send the value as metric to Dynatrace. Or build a oneagent extension. There are several options.